Company Portrait

Amphasys was founded in 2012 as a spin-off from Axetris AG, a company of the Leister group. The company focuses its activities in developing and marketing a novel, chip-based single cell analysis technology. Amphasys' mission is to simplify, speed up and miniaturize complex cell analyses and move them to the point-of-use, which may be outside well-equipped research and analytical laboratories. The basic technology has been developed in 2004 in collaboration with the Swiss Federal Institute of Technology Lausanne (EPFL). Consequently, several years of research with different cell types proved that the technology is suitable for a wide array of applications. So far, two of the most promising fields turned out to be analysis of pollen and milk. In 2013 Amphasys was awarded with the most prestigious Swiss startup price by the W.A. de Vigier Foundation. Amphasys was also supported by the Albert Koechlin Foundation and certified by CTI Invest®. Today, Amphasys is a speedily growing high tech company dedicated to reinventing single cell analysis and applying it to industrial production processes.

Management (Geschäftsleitung)

Dr. Marco Di Berardino
Executive Partner
Head Research, Development & Production (CTO)

Dr. Marcel Ottiger
Executive Partner
Head Corporate Functions (CFO, CSO)

Board of Directors (Verwaltungsrat)

Dr. Marco Di Berardino, Chairman
Marco received his PhD in Natural Sciences at the Swiss Federal Institute of Technology Zurich (ETH Zurich) in 1996. After his postdoctoral fellowship at F. Hoffmann-La Roche he worked as project manager and business developer in two start-up companies. During that time he obtained his bachelor degree in business administration at the GSBA Zurich. At Axetris AG, a company of the Leister Group, Marco led the development of the Impedance Flow Cytometer from the feasibility to the prototype and raised the awareness for this technology to the cytometry community through numerous publications and presentations. In 2012 he co-founded Amphasys as a spin-off from Axetris AG.

Dr. Marcel Ottiger, Vice President of the Board of Directors
Marcel graduated with a PhD degree in Molecular Biology and Biophysics (1996) in the group of nobel prize winner Prof. Dr. Kurt Wüthrich at the Swiss Federal Institute of Technology Zurich (ETH Zurich). He continued his studies with nuclear magnetic resonance at the National Institutes of Health, USA. Back in Switzerland, he joined COMIT as an IT consultant in 1999 and received his degree as executive MBA at the University of St.Gallen (2004). After the company was acquired by Swisscom IT Services, he was promoted to the executive board in which role he was responsible for a business unit consisting of up to 300 consultants. In addition, he was partner at Mecon Measure & Consult GmbH between 2000 and 2012. Marcel was one of the co-founders of Amphasys and joined the company as Executive Partner in January 2014.

Thomas Bergen
Thomas got his business and economics degree in 1993 from the University of St.Gallen. He was vice president at Migros Bank. In 1999, Thomas co-founded getAbstract. As CEO, he is running the global business of getAbstract from the Lucerne headquarters. From 2003 until 2011, he served as a member of the board of the Swiss Management Association, which he presided for the last two years. He is also a member of the foundation council of the famous monastery in Einsiedeln, lectured on entrepreneurship at the University of St.Gallen and is one of the co-founders of Amphasys.

Christiane Leister
Christiane Leister studied economics at the Christian-Albrechts-Universität, Kiel, Germany. During the first ten years of her career she worked with well-known German family enterprises and thereby developed deep knowledge in finance and controlling. Between 1989 and 1993 she was responsible for executive and strategic assignments in the Leister family enterprise. In succession, she further developed the single enterprise on the basis of new technologies und business activities to the Leister group including eleven companies in three continents. In 1998, Christiane Leister started with activities in the area of microtechnology for gas sensors and micro optics which was then developed to Axetris AG, a subsidiary of the Leister group. In 2016 she was elected by the Swiss Federal Council to become a member of the ETH board (board of the Swiss Federal Institute of Technology).

Heiner Scherrer
Heiner got his diploma as a mechanical engineer at the Swiss Federal Institute of Technology Zurich (ETH Zurich). After two years as assistant professor at ETH he started his own engineering company. In 1985 he co-founded CTC Analytics where he is still engaged as chairman. Heiner joined the board of Amphasys as investor to contribute his knowledge in the design, production and distribution of scientific instruments.

Scientific Board

Prof. Dr. Philippe Renaud
Philippe was appointed as professor at the Swiss Federal Institute of Technology Lausanne (EPFL) (Microsystems Laboratory) in 1997. Philippe is also the scientific director of the EPFL Center of MicroNanoTechnology (CMI). His main research area is related to micronano technologies in biomedical applications (BioMEMS) with emphasis on cell-chips, nanofluidics and bioelectronics. Philippe is committed to valorisation of basic research through his involvement in several high-tech start-up companies.

Dr. Iris Heidmann 
Iris is CEO and senior researcher on plant cell biology at Acepo, Enkhuizen (NL). Her research and services focuse on pollen viability analysis, plant regeneration systems from somatic and generative cells, mutagenesis and epigenetics. She completed her PhD studies at Wageningen University. Before Acepo, she worked for many years at Enza Zaden and at various research institutes in Germany (Inst. for Horticultural Plant Breeding, Ahrensburg; University of Konstanz, Max-Planck Institute of Plant Breeding Research Cologne). Iris’ knowledge about pollen development and her initial exploitation of Amphasys’ impedance flow cytometer for pollen analysis was essential for all further developments in this field.

Dr. Ladislav Kucera
Ladislav received his PhD in electrical engineering from the Swiss Federal Institute of Technology Zurich (ETH Zurich) in 1997. After working as Director Electronics & Control at ESEC AG, where he was leading more than 50 engineers, he founded his own company, Triamec Motion AG. He is an expert in HF Signal Processing, has a profound theoretical background of impedance analysis and a compelling experience in the programming of embedded systems. Ladislav was instrumental in developing Amphasys' electronics hardware for the impedance flow cytometer.

References

Enza Zaden, NL
Joep Lambalk, R&D Director: “At Enza Zaden, analysis of pollen viability by microfluidic impedance flow cytometry is developing into a standard method helping to improve breeding technologies and the yield of seed production. The method relies on easy and standardized protocols resulting in much faster, objective and more reproducible results than with other methods. In addition, one of its biggest advantages lies in the continuous monitoring of pollen quality directly at the production site providing better control over the production chain. It thereby helps to prevent production losses due to pollination with inferior pollen. Control over pollen quality is even more important when working with contractors.”

Translationszentrum für Regenerative Medizin - TRM Leipzig
Prof. Attila Tárnok: “My group develops diagnostic tools to enable predictive medicine for personalized therapy. Presently, cell analysis by flow cytometry is the method of choice as it allows maximum information yield from small blood sample volumes but requires staining. This is where the Amphasys impedance flow cytometer has a huge potential over conventional flow cytometry providing label-free fingerprinting of cellular phenotype and function. This will lead to innovative cellular diagnostic tools that need minute sample volumes and are cost effective.”

Careers – open positions

Amphasys is a fast-growing and aspiring company with very ambitious goals. Consequently, we are looking for dynamic, talented and open-minded people who are committed and motivated to influence their own development and step beyond the mass. Feel free to send us your CV and your motivations for working in the exciting field of impedance-based single cell analysis.